Hmm... there are a lot of mixed genres these days. The Total War series is both turn-based and real-time. Warcraft 3, Spellforce is certainly RPG-RTS. UFO Aftershock is somewhat RPG-TBS. Dominions, X-Com 1 and 2 are RPG-Turn based strategy. X-Com 3 is RPG-TBS-RTS. X-Com 4 is Flight Sim-RPG-TBS. Some sports games also have lots of RPG elements, management/trading in them. I played NBA Live 07 as a manager on my friend's comp, replaced almost all the Boston Celtics players, lol.
So... should we just get rid of genres? Then how would we search for games we like?
Disclaimer: Any sarcasm in my posts will not be mentioned as that would ruin the purpose. It is assumed that the reader is intelligent enough to tell the difference between what is sarcasm and what is not.